Caseating Granulomas in Cutaneous Leishmaniasis
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چکیده
منابع مشابه
Caseating Granulomas in Cutaneous Leishmaniasis
BACKGROUND Caseating granulomas are often associated with a mycobacterial infection (TB) and are thought to be exceedingly rare in cutaneous leishmaniasis (CL). However, no large series has accurately documented the incidence of caseating granulomas in CL. METHODS A multiregional cohort consisting of 317 patients with CL [Syria (157), Pakistan (66), Lebanon (47), Saudi Arabia (43), Ethiopia (...
متن کامل[Cutaneous leishmaniasis].
Cutaneous leishmaniasis is endemic in certain tropical and sub-tropical regions, and is sometimes encountered as an imported disease in Norway. The disease is characterized by chronic and painless, but often disfiguring, ulcers that regress after some months to years, leaving atrophic scars. Diagnosis is established by demonstrating amastigote Leishmania bodies by microscopy of Giemsa-stained s...
متن کاملCutaneous Leishmaniasis
Transforming growthfactor (TGF)-,8 has several downregulatoryfunctions on the immune systenm inhibition ofinterleukin-2 receptor induction, decrease of interferon-yinduced class II antigen expression, inhibition of macrophage activation, as weUl as cytotoxic and lymphokineactivated kilter cell generation. TGF-(8 has also been recognized as an important immunoregulator in murine leishmaniasis, f...
متن کاملCutaneous leishmaniasis.
Cutaneous leishmaniasis is endemic in the tropics and neotropics. It is often referred to as a group of diseases because of the varied spectrum of clinical manifestations, which range from small cutaneous nodules to gross mucosal tissue destruction. Cutaneous leishmaniasis can be caused by several Leishmania spp and is transmitted to human beings and animals by sandflies. Despite its increasing...
متن کاملCutaneous Leishmaniasis in Syria
Cutaneous leishmaniasis (CL) is a public health problem in Syria call for this parasite’s epidemiological and evolutionary investigation. Evaluation of its population structure by multilocus enzyme electrophoresis (MLEE), current gold standard for classification, has some drawbacks ,such as the lack of discriminatory power below species level, it is labour intensive and time-consuming. In this ...
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ژورنال
عنوان ژورنال: PLoS Neglected Tropical Diseases
سال: 2014
ISSN: 1935-2735
DOI: 10.1371/journal.pntd.0003255